Dr. Qiana Matthews

Dr. Qiana Matthews
Assistant Professor of Microbiology
Dept. of Biological Sciences
E-mail: qmatthews@alasu.edu
Phone: 334-229-8449

Our laboratory interest include: (i) developing gene therapy models that will contribute to the advancement of biomedical sciences and human health. (ii) developing safe and effective vaccines for infectious diseases. Our research concentrates on the scientific investigation of human disease, specifically, disease pathogenesis and vaccine development related to HIV-1, Chagas disease and Zika Fever. In regard to our vaccine efforts, we focus on genetically modifying adenoviral vectors and human exosomes to be used as vaccine delivery vehicles for human disease reduction or elimination.

Selected Publications

1: Sims B, Farrow AL, Williams SD, Bansal A, Krendelchtchikov A, Gu L, Matthews QL. Role of TIM-4 in exosome-dependent entry of HIV-1 into human immune cells. Int J Nanomedicine. 2017 Jul 6;12:4823-4833. doi: 10.2147/IJN.S132762.

eCollection 2017. PubMed PMID: 28740388; PubMed Central PMCID: PMC5505621.

2: Gu L, Sims B, Krendelchtchikov A, Tabengwa E, Matthews QL. Differential

binding of the HIV-1 envelope to phosphatidylserine receptors. Biochim Biophys

Acta. 2017 Oct;1859(10):1962-1966. doi: 10.1016/j.bbamem.2017.06.007. Epub 2017 Jun 13. PubMed PMID: 28622976; PubMed Central PMCID: PMC5593811.

3: Matthews QL, Farrow AL, Rachakonda G, Gu L, Nde P, Krendelchtchikov A, Pratap S, Sakhare SS, Sabbaj S, Lima MF, Villalta F. Epitope Capsid-Incorporation: New Effective Approach for Vaccine Development for Chagas Disease. Pathog Immun. 2016 Fall-Winter;1(2):214-233. PubMed PMID: 27709126; PubMed Central PMCID:


4: Gu L, Icyuz M, Krendelchtchikova V, Krendelchtchikov A, Johnston AE, Matthews QL. Development of an Ad5H3 Chimera Using the "Antigen Capsid-Incorporation" Strategy for an Alternative Vaccination Approach. Open Virol J. 2016 Apr

26;10:10-20. doi: 10.2174/1874357901610010010. eCollection 2016. PubMed PMID:27335626; PubMed Central PMCID: PMC4892130.

5: Farrow AL, Peng BJ, Gu L, Krendelchtchikov A, Matthews QL. A Novel Vaccine Approach for Chagas Disease Using Rare Adenovirus Serotype 48 Vectors. Viruses. 2016 Mar 10;8(3):78. doi: 10.3390/v8030078. PubMed PMID: 26978385; PubMed Central PMCID: PMC4810268.