Dr. Manoj K. Mishra

Mishra Headshot

Manoj K. Mishra, Ph.D.
Professor of Biology
Director, Cancer Biology Research and Training Program
Director, Freshman Biology Program
Department of Biological Sciences
Email: mmishra@alasu.edu
Tel: 334-604-8410

 

 

Biography

Dr. Mishra received his M.Sc. and Ph.D. from Banaras Hindu University, Varanasi, India. After obtaining his doctorate, he moved to the USA and did his postdoctoral training in the Division of Biology, Kansas State University, Manhattan, KS; Division of Allergy and Immunology, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO; and Division of Rheumatology, Department of Pediatrics at Medical College of Wisconsin, Milwaukee, WI. Before moving to Alabama State University in early 2009, Dr. Mishra continued at the Medical College of Wisconsin as a Research Scientist in the Division of Allergy and Clinical Immunology within the Department of Pediatrics. Dr. Mishra also holds a secondary appointment at the Division of Molecular and Cellular Pathology within the Department of Pathology, School of Medicine at the University of Alabama Birmingham, Birmingham, AL. Dr. Mishra serves on several NIH study sections and the editorial board of scientific peer-reviewed journals. Research and educational grants from the National Institutes of Health and the National Science Foundation support Dr. Mishra's lab. Dr. Mishra has several awards and recognition for his teaching and research. In 2015, he received the Faculty of the Year award at Alabama State University. In 2013, he was selected as one of the top 25 professors among mid-sized universities in the USA. He was a faculty scholar in cancer research at the American Association of Cancer Research in 2013, 2014, and 2016. In 2022, Dr. Mishra received outstanding achievement awards from the Society of American Asian Scientists in Cancer Research (SAASCR). Dr. Mishra is the founding director of the Cancer Biology Research and Training program; and the founding director of the Freshmen Biology program at Alabama State University. Dr. Mishra's education interest revolves around training, mentoring, and providing opportunities to undergraduate and graduate students, mainly from underrepresented populations. His research interest focuses on broader areas of immunology, tumor biology, and health disparity, using prostate cancer as a model system. Dr. Mishra's lab currently investigates the roles of dietary compounds, microbial metabolites, and immune cells, especially regulatory T and NK cells, in prostate cancer development and progression.

Research Interests

Role of immune cells in prostate cancer: Prostate Cancer (PCa) is the most common non-skin malignancy and commonly diagnosed cancer and the second most cancer responsible for death in men in the United States. Prior studies in animal models of PCa and in humans demonstrated that the prostate produces several growth factors. Adding or blocking these growth factors can alter PCa cell proliferation and other important functions. Among these growth factors, transforming growth factor-β1 (TGF-β) plays a significant role in tumorigenicity, displays potent immunosuppressive activities, and is required to convert conventional CD4+ T cells to FoxP3+ regulatory T cells (TR). TR that expresses the transcription factor Foxp3 is essential for normal immune function. The absence of TR cells results in multi-organ autoimmunity and death. A clear role of TGF-β and its effect on TR during PCa lacks experimental evidence. In this project, we investigate the underlying mechanisms involved in the context of TGF-β and/or TR using PCa cell lines derived from the transgenic mouse for prostate cancer (TRAMP) in C57/B6 mice. These cell lines, TRAMP-C1 and TRAMP-C2, form tumors, while TRAMP-C3 fails to form tumors. The objective of this project is to define the role of TGF-β production by host cells in response to or TGF-β expression by TRAMP cell lines and to analyze the role of TGF-β in the conversion of naïve CD4+ T cells to Foxp3 expressing TR cells. 

Role of dietary compounds in controlling prostate cancer development and progression: Our current research interest is understanding the molecular mechanism(s) involved in prostate cancer development and clearance in response to a dietary compound, resveratrol (RES). Resveratrol is a polyphenolic compound found in the skin of red fruits and exhibits anti-inflammatory, anti-oxidative, anti-cancer, and anti-proliferative characteristics. RES was first detected in the dried roots of Polygonum cuspidatum, traditionally used in Chinese and Japanese medicines as an anti-inflammatory agent. This project explores the role of RES on NK cells and macrophages, particularly the tumor-associated macrophages (TAM) and regulatory T cells in the tumor microenvironment.

 

Current Lab members

Ritish Shyanti, Ph.D., Research Scientist

ritisDr. Ritis Shyanti is working as a Research Scientist in the Cancer Biology Research and Training Program (CBRT), Biological Sciences at Alabama State University (ALASU). His research is focused on basic biomedical science in cancer biology and training students in biomedical techniques. He has a broad background in cancer biology research and drug screening on different cancer models (in vitro and in vivo).

Project Title: NKT (Natural Killer T) cells dependent and independent CD1d interaction and its impact on breast cancer.

Dr. Shyanti was recently awarded the Clinical Scientist Developmental Grant funded by the American Cancer Society. The project is focused on "Exploring CD1d's Function in Regulating Breast Cancer Pathophysiology," which can significantly enhance our comprehension of breast cancer metastasis and resistance to therapy. The study concentrates on the role of CD1d in disease progression through the direct or indirect modulation of Natural Killer T cells and identifying CD1d's potential in both detection and therapeutics. Besides this, he is working on cancer stem cells, metastasis, and drug resistance associated with prostate, colon, and breast cancers. Further, his idea is to explore the targeted therapy that can be achieved by using phytochemicals and drugs that selectively target cancer, and cancer stem cells and improve tumor immunity.

Nivedita Priyadarshini, Ph.D., Research Scientist

NiveditaDr. Priyadarshni did her Ph.D. at the Academy of Scientific and Innovative Research (CSIR-CMERI Academic Campus), India. After obtaining her doctorate, she worked as an Assistant Professor at the Department of Biotechnology, Patna Women’s College, India. In December 2022’ she moved to the USA and joined the Cancer Biology Research and Training (CBRT) Department of Biology at Alabama State University as a Postdoctoral Researcher. Currently, she is working as Research Scientist in CBRT focusing on the development of noble nanoparticle-based drug carriers and biosensors for the diagnosis of cancer at an early stage.

RESEARCH INTERESTS: She is working on the development of methodologies for early diagnosis, prevention, and regression of cancer and studying the mechanism/pathway of tumor suppression. She has expertise in the synthesis, characterization, and surface functionalization of nanomaterials and their utilization in the development of rapid, cost-effective, and easily operable chemo/biosensors. Currently, she is working to develop an early-stage diagnosis kit for lung and breast cancer with the help of liquid biopsy. Her research also focuses on synthesizing nanoparticles with essential elements and studying their effect on prostate cancer cells and related to the influential role of immune cells on outcomes.

Mazharul Haque, Ph.D., Postdoctoral fellow

mazDr. Mazharul Haque, received his master's degree in Biotechnology and Ph.D. from the Center for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India. Then he moved to Alabama State University, USA, and worked as a postdoctoral research associate his current research interest is the study of the Molecular interplay of epigenetic alteration in the regulation of downstream genes in tumorigenesis and ascertain potential therapeutic approaches to attenuate cancer cell progression. His other research interests include the design and development of 3D scaffolds for tissue regeneration and its application in wound healing and cancer.

 

Ibrahim Alamin, Microbiology Ph.D. candidate

IbrahimResearch Project: Investigating the therapeutic potential of microbiomes in modulating colorectal cancer.

Education:

Master of Medical Microbiology, University of Khartoum, Khartoum, Sudan, 2015.

Bachelor of Medical Laboratory Science, Omdurman Ahlia University, Omdurman, Sudan, 2009.

Research Interest: Demonstrate the molecular mechanisms of colorectal cancer signaling pathways that could be targeted as a therapeutic intervention and drug development by applying transcriptomics, metabolomics, and proteomics analysis.

 

 

Azura Murphy, MS candidate

 

Past Lab Members

Shalie Malik, Ph.D.: Dr. Malik is currently a Professor of Zoology at the University of Lucknow, India. She is also the director of Dr. Giri Lal Gupta Institute of Public Health and Public Affairs at the University of Lucknow.

James Stokes III, Ph.D.: Dr. Stokes works as Scientist II at AbbVie.

Sanjay Kumar, Ph.D.: Dr. Kumar is working as a scientist at Southern Research Institute.

Chand B. Davuljigari, Ph.D.: Current designation not available.

Anurag Singh, Ph.D.: Dr. Singh is a research associate at the Indian Institute of Technology at Banaras Hindu University, India.

Brittany Hollins, MS: Ms. Hollins is a biology instructor at Alabama State University.

Eric Berry II, MS: Mr. Berry is a laboratory technician at BioEnergy in Memphis, TN.

 

Current Active Grants/Funding

1. DICRIDG-22-1037199-01DICRIDG) (Mishra-PI), 01/01/2023-12/31/2026, American Cancer Society ($2.7M)

Enhancing Cancer Research Capacity at Alabama State University

This proposal aims to enhance the overall cancer research capacity at ASU.

2. 1 R25 AG070244-01A1, (Mishra-PI), 09/01/2022-08/31/2027, NIH/NIA

Alabama State University-Auburn University Partnership to Promote Diversity in Aging Research ($1.45M)

The overarching objectives of the proposal are 1) To develop educational Geo-Information System (GIS) modules and their impact on aging research and 2) to provide academic and summer research experiences to STEM undergraduate students.

3. AIM-AHEAD NIH (Suman-PI, Mishra-Site PI), 09/01/2022-02/28/2024, NIH/NIMHD

Pilot proposal: Evaluating bias in predictive and explainable ML algorithms among older adults with cancer. ($74K)

The objectives and goal of this proposal are based on analyzing data using GIS and understanding how this data helps in advancing health equity and reducing cancer disparity.

4. U01 GM132769-01, (Mishra-PI),  07/01/19-06/30/24, NIH/NIGMS
Intersection of Social Capital, Mentorship and Networking on Persistence, Engagement and Science Identity ($2.9M)

The overarching objectives of this proposal are to test: 1) the effects of pre-existing personal and contextual factors on the participation of undergraduate students from diverse backgrounds in the biomedical workforce, 2) test whether mentoring/networking intervention, mainly in first-year students and sophomore years, influence the persistence, engagement, and development of science identity of students from diverse backgrounds. Our proposal focuses on Historically Black Colleges and Universities (HBCUs) geographically distributed with different individual- and neighborhood-level socioeconomic factors.

5. 1912322, (Mishra-PI), 07/01/19-04/30/24 (NCE), National Science Foundation                 

Transforming Biology Laboratory Learning by the Development, Deployment, and Assessment of evidenced-based research and learning (EBRL) experiences($400K)                                        The main goal of this proposal is to design an evidence-based curriculum at ASU and to provide research interventions to underserved freshmen/sophomore students in cutting-edge research in biomedical disciplines.

 

Completed Grants/Funding

Grant Number: AEOP-REAP, Funding agency: Army Educational programs-Research and Engineering Apprenticeship Program, Title: The Research and Engineering Apprenticeship Program (REAP) at Alabama State University, Role: REAP site Project Director, Duration: 2018-2021, Goal: The main goal of this project was to train and expose high school students during the summer to cancer research.

Grant Number: 1510479, Funding agency: National Science Foundation, Title: RUI: Spatially and Compositionally Gradient Scaffolds for Anterior Cruciate Ligament, Role: Co-Principal Investigator, Duration: 08/01/2015-08/31/2020, Goal: To conduct biomedical research

Grant Number: P20CA192976, Funding Agency: National Cancer Institute, National Institutes of Health Institute, Title: 2/2 Alabama State University/UAB Comprehensive Cancer Center partnership (P20), Role: Principal Investigator, Duration: 10/01/2014-09/30/2019, Goal: The main objective of this proposal was to foster partnership with 'UAB's comprehensive cancer center and start a cancer research, education, and training program at Alabama State University in the areas of colorectal and prostate cancer to eliminate health disparity in minority populations.

Grant Number: PC150726, Funding Agency: US Department of Defense, Title: Diversifying Biomedical Researchers in Prostate Cancer through Academic Affiliations between UNTHSC and Alabama State University, Role: Co-Principal Investigator, Duration: June 2016-July 2019, Goal: The project provided training to 16 undergraduate STEM students during summer in prostate cancer research at UNTHSC.

Grant Number: ASU-CON PARTNER, Funding agency: Conversant Bio, Title: Alabama State University-Conversant Bio Partnership, Role: Principal Investigator, Duration: 2014-2019, Goal: This project fostered a partnership between academia and industry to engage undergraduate and graduate students in cancer research.

Grant Number: W911NF-14-1-0064, Funding agency: US Department of Defense, Title: Acquisition of a flow cytometry system to enhance undergraduate research and STEM education, Role: Principal Investigator, Duration: 01/01/2014-12/31/2016, Goal: The primary purpose of this project was to acquire a flow cytometer to enhance research and education at Alabama State University.

Grant Number: LICOR-ODYSSEY, Funding agency: LiCor Biosciences, Title: Science Undergraduate Research Award, Role: Principal Investigator, Duration: March 2016-December 2016, Goal: The primary purpose of this project was to acquire an Odyssey imaging system to enhance research and education at Alabama State University.

Grant Number: W911NF-12-1-0073 supplement, Funding agency: US Department of Defense, Title: URAP supplement: Multifunctional Polymeric Scaffolds for Bone-Tissue Regeneration, Role: Principal Investigator, Duration: Summer of 2015 and 2016, Goal: The main objective of this project was to train and expose undergraduate STEM students during summer in the area of bone-tissue regeneration and cancer research.

Grant Number: W911NF-12-1-0073, Funding Agency: US Department of Defense, Title: Multifunctional Polymeric Scaffolds for Bone-Tissue Regeneration, Role: Principal Investigator, Duration: 2/24/2012-2/23/2016, Goal: The main goal of this proposal was to develop scaffolds that mimic the characteristics of the Extracellular matrix and its role in molecular pathways in bone tissue regeneration processes.

Grant Number: W911NF-12-1-0073 HSAP supplement, Funding agency: US Department of Defense, Title: HSAP supplement: Multifunctional Polymeric Scaffolds for Bone-Tissue Regeneration, Role: Principal Investigator, Duration: Summer of 2015 and 2016, Goal: The primary purpose of this project was to train and expose undergraduate STEM students during summer to bone-tissue regeneration and cancer research.

Grant Number: 1154214, Funding Agency: National Science Foundation, Title: Scholarships to promote retention and graduation rates in STEM Disciplines, Role: Principal Investigator, Duration: 9/15/2012-8/31/2018, Goal: The main goal of this proposal was to provide scholarships to undergraduate STEM students to increase the graduation and retention rate at Alabama State University. This grant provided scholarships to 130 STEM undergraduate students and supported tutoring services at ASU.

Publications (2009-Onwards)

  1. Shalie Malik, James Stokes III, Upender Manne, Rajesh Singh, Manoj K.Mishra (2022) Understanding the  significance of biological clock and its impact on cancer incidence. Cancer Letters, Volume 527, 28 February 2022, Pages 80-94
  2. Seela Aladuwaka, Ram Alagan, Rajesh Singh, Manoj K Mishra (2022) Health Burdens and SES in Alabama: Using Geographic Information System to Examine Prostate Cancer Health Disparity. Cancers, 9/2022, 14(19), 4824; https://doi.org/10.3390/cancers14194824
  3. James Stokes III, Sankalp Vinayak, Jazalyn Williams, Shalie Malik, Rajesh Singh, Upender Manne, Taofeek K. Owonikoko, Manoj K. Mishra (2021) Optimum health and inhibition of cancer progression by microbiome and resveratrol. Frontier of Biosciences Front Biosci (Landmark Ed) 2021 January 1;26:496-517.
  4. Bassel Nazha, Subir Goyal, Zhengjia Chen, Anne Engelhart, Jennifer Wilkinson Carlisle, Tyler Beardslee, Harpaul Gill, Levani Odikadze, Yuan Liu, Manoj K. Mishra, Suresh S. Ramalingam, Taofeek Kunle Owonikoko (2020) Efficacy and safety of immune checkpoint blockade in self-identified Blacks with advanced non-small cell lung cancer (NSCLC). Cancer. DOI: 10.1002/cncr.33141.
  5. Santosh K. Singh, Manoj K. Mishra, Brian M. Rivers, Jennifer B. Gordetsky, Sejong Bae, and Rajesh Singh (2020) Biological and Clinical Significance of the CCR5/CCL5 Axis in Hepatocellular Carcinoma. Cancers (Basel). Cancers, Apr; 12(4): 883.
  6.   Bassel Nazha, Manoj Mishra, Rebecca Pentz, and Taofeek K. Owonikoko (2019) Enrollment of Racial Minorities in Clinical Trials: Old Problem Assumes New Urgency in the Age of Immunotherapy. American Society of Clinical Oncology Educational Book, Volume 39, pages: 3-10.
  7. Santosh Kumar Singh, Manoj Kumar Mishra, Rajesh Singh (2019) Hypoxia-inducible factor-1α induces CX3CR1 expression and promotes the epithelial to mesenchymal transition (EMT) in ovarian cancer cells. J Ovarian Res.  2019 May 10;12(1):42.
  8. Abron JD, Singh NP, Murphy AE, Mishra MK, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP (2018) Differential role of CXCR3 in inflammation and colorectal cancer. Oncotarget. 9(25):17928-17936 PMID: 29707158.
  9. Abron JD, Singh NP, Mishra MK, Price RL, Nagarkatti M, Nagarkatti PS, Singh UP (2018) An endogenous aryl hydrocarbon receptor (AhR) ligand, ITE induces regulatory T cells (Tregs) and ameliorates experimental colitis. Am J Physiol Gastrointest Liver Physiol. DOI: 10.1152/ajpgi.00413.2017 PMID: 29672155.
  10. Andrew Wood, Dominique Everett, Sanjay Kumar, Manoj Mishra, and Vinoy Thomas (2018) Fiber Length and Concentration: Synergistic Effect on Mechanical and Cellular Response in Wet-Laid poly(lactic acid) Fibrous Scaffolds. J Biomed Mater Res B Appl Biomater. DOI: 10.1002/jbm.b.34125 PMID: 29656479.
  11. Sanjay Kumar, Sanjeev Gurshaney, Yori Adagunodo, Erica Gage, Shezreen Qadri, Mahak Sharma, Shalie Malik, Upender Manne, Udai P. Singh, Rajesh Singh, Manoj K. Mishra (2018). Hsp70 and γ-Semino Protein as possible prognostic markers of prostate cancer. Frontiers in Biosciences. 987-2000.
  12. Singh SK, Mishra MK, Eltoum IA, Bae S, Lillard JW Jr., Singh R. (2018) CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells. Sci Rep. 2018 Jan 22;8(1):1323. PMCID: PMC5778036
  13. Sanjay Kumar, Rajesh Singh, Shalie Malik, Upender Manne, Manoj Mishra (2017) Prostate cancer health disparities: An immuno-biological perspective. Cancer Letters. 414:153-165, PMID: 29154974.
  14. Bo Wang, Wuwei Li, Derrick Dean, Manoj K. Mishra, and Kennedy S. Wekesa (2017) Enhanced Hepatogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells on Liver ECM Hydrogel. Journal of Biomedical Materials Research Part A. Published online on October 25, 2017, DOI: 10.1002/jbm.a.36278
  15. Sanjay Kumar, James Stokes III, Udai P Singh, Karyn Scissum-Gunn, Rajesh Singh, Upender Manne, Manoj K Mishra (2017) Prolonged exposure of resveratrol induces reactive superoxide species–independent apoptosis in murine prostate cells. Tumor Biology. 39(10): 1-10. DOI: 10.1177/1010428317715039 [PMCID not found]
  16. Kumar S, Eroglu E, Stokes III JA, Gunn KS, Saldanha SN, Singh UP, Manne U, Ponnazhagan S, Mishra MK. (2017) Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells. Oncotarget. 8(13):20895-20908, PMCID: PMC5400554
  17. Shamran H, Singh NP, Zumbrun EE, Murphy A, Taub DD, Mishra MK, Price RL, Chatterjee S, Nagarkatti M, Nagarkatti PS, Singh UP (2017) Fatty acid amide hydrolase (FAAH) blockade ameliorates experimental colitis by altering microRNA expression and suppressing inflammation. Brain, Behavior, and Immunity. 59:10-20, PMCID: PMC5154806
  18. Sanjay Kumar, James A. Stokes III, Derrick Dean, Christian Rogers, Elijah Nyario, Vinoy Thomas, and Manoj K. Mishra (2017) Biphasic organo-bioceramic fibrous composite as a biomimetic extracellular matrix for bone tissue regeneration. Frontiers in Biosciences. 9: 192-200. PMID: 28199184
  19. Anil Shanker, Menaka Thounaojam, Manoj K Mishra, Mikhail M Dikov (2017) Innate-Adaptive Immune Crosstalk 2016. Journal of Immunology Research. 1-2. PMCID: PMC5405582
  20. Sanjay Kumar, James Stokes III, Udai P. Singh, Karyn Scissum Gunn, Arbind Acharya, Upender Manne, Manoj Mishra (2016) Targeting Hsp70: A possible cancer therapy. Cancer letters. 374:156–166. PMID: 26898980
  21. Anil Shanker, Menaka C Thounaojam, Manoj K. Mishra, Mikhail M. Dikov and Roman V. Uzhachenko (2015) Innate-Adaptive Immune Crosstalk. Journal of Immunology Research. 1-2. PMCID: PMC5405582
  22. Maria Teresa P. de Aquino, Anshu Malhotra, Manoj K. Mishra, and Anil Shanker (2015) Challenges and future perspectives of T cell immunotherapy in cancer. Immunology Letters. 19; 166(2):117-133. PMCID:PMC4499494
  23. Udai P. Singh, Angela E. Murphy, Reilly T. Enos, Haidar A. Shamran, Narendra P. Singh, Honbing Guan, Venkatesh L. Hegde, Daping Fan, Robert L. Price, Dennis D. Taub, Manoj K. Mishra, Mitzi Nagarkatti,  and Prakash S. Nagarkatti (2014) MicroRNA-155 deficiency protects mice from experimental colitis by reducing Th1/Th17 responses. Immunology. 143(3):478-489. PMCID:PMC4212960
  24. Amanee D. Salaam, Manoj K. Mishra, Elijah Nyairo, and Derrick R. Dean. (2014) Electrospun polyvinyl alcohol/nanodiamond composite scaffolds: morphological, structural, and biological analysis. Journal of Biomaterials and Tissue Engineering. 4:73-180. DOI: 10.1166/jbt.2014.1152
  25. Singh UP, Singh NP, Guan H, Busbee B, Price RL, Taub DD, Mishra MK, Fayad R, Nagarkatti M, Nagarkatti PS. (2014) The Emerging Role of Leptin Antagonist as Potential Therapeutic Option for Inflammatory Bowel Disease. Int Rev Immunol. 33:(1):23-33. PMCID:PMC4159716
  26. James Stokes III, Udai P. Singh, Elijah Nyairo, Manoj K. Mishra (2013) Resveratrol and its impact on Prostate cancer. International Journal of Advanced Biotechnology & Bioinformatics. 2:6-13. [not found]
  27. Erica G. Schmitt, Dipica Haribhai, Jonathan C. Jeschke, Dominic O. Co, Jennifer Ziegelbauer, Ke Yan, Yoichiro Iwakura, Manoj K. Mishra, Pippa Simpson, Nita H. Salzman, and Calvin B. Williams (2013) Chronic Follicular Bronchiolitis Requires Antigen-Specific Regulatory T Cell Control to Prevent Fatal Disease Progression. Journal of Immunology. 191:5460-5476. PMCID: PMC3893829
  28. Udai P. Singh, Narendra P. Singh, Honbing Guan, Venkatesh L. Hegde, Robert L. Price, Dennis D Taub, Manoj K. Mishra, Mitzi Nagarkatti,  & Prakash S. Nagarkatti (2013) The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment. PLOS One, 8(11):e79751. PMCID: PMC3836899
  29. Singh UP, Singh NP, Guan H, Busbee B, Price RL, Taub DD, Mishra MK, Fayad R, Nagarkatti M, Nagarkatti PS. (2013) Leptin antagonist ameliorates chronic colitis in IL-10-/- mice. Immunobiology. 218(12):1439-1451. PMCID: PMC3778116
  30. Udai P. Singh, Narendra P. Singh, Brandon Busbee, Guan, H, Robert L. Price, Dennis D. Taub, Manoj K. Mishra, Mitzi Nagarkatti, and Prakash S. Nagarkatti (2012) Microbial Links to Inflammatory Bowel Disease Development: Potential Interventional Strategies in Treatment. Journal of Bacteriology and parasitology. 3:7. [not found]
  31. Renu Bhatt, Vinoy Thomas, Derrick Dean, Elijah Nyairo, Udai P. Singh, and Manoj K. Mishra (2012) Role of PPARs as Chemotherapeutics and Anticancer molecules. International Journal of Advanced Biotechnology & Bioinformatics. 1:11-18. [not found]
  32. Himani D. Deshpande, Derrick R. Dean, Vinoy Thomas, William C. Clem, Moncy V. Jose, Elijah Nyairo, and Manoj K. Mishra. (2012) Carbon nanofiber reinforced polycaprolactone fibrous meshes by electrostatic co-spinning. Current Nanoscience. 8(6):753-761. DOI: 10.2174/157341312802884409
  33. Amanee Salaam, Manoj K. Mishra, Elijah Nyairo, and Derrick Dean (2012) Morphological and Biological Characterization of PVA-Nanodiamond Electrospun Fibers. Polymeric Materials: Science and Engineering. 106:334-335. doi:10.1166/jbt.2014.1152
  34. Udai P. Singh, Narendra P. Singh, Brandon Busbee, Guan, H, Balwan Singh, Robert L. Price, Dennis D. Taub, Manoj K. Mishra, Mitzi Nagarkatti, and Prakash S. Nagarkatti (2012) Alternative medicines as emerging therapies for inflammatory bowel diseases. International Reviews of Immunology. 31(1):66-84. PMCID: PMC4138959
  35. Himani Deshpande, Carrie Schindler, Derrick Dean, William Clem, Susan Bellis, Elijah Nyairo, Manoj K. Mishra, Vinoy Thomas (2011) Nanocomposite scaffolds based on electrospun polycaprolactone/modified carbon nanofiber/ nanohydroxyapatite by electrophoretic deposition. Journal of Biomaterials and Tissue Engineering. 1:177-184. DOI: 10.1166/jbt.2011.1024
  36. Udai P. Singh, Narendra P. Singh, Balwan Singh, Manoj K. Mishra, Mitzi Nagarkatti, Prakash S. Nagarkatti, and Singh S.R. (2010) Stem Cell in Inflammatory Bowel Disease and its Therapeutic Implication. Frontiers in Bioscience. 1(2):993-1008. [not found]
  37. Srikanta Jana, Parthav Jailwala, Dipica Haribhai, Jill Waukau, S Glisic, William Grossman, Manoj K. Mishra, Ren Wen, D Wang, Calvin B Williams, S Ghosh. (2009) The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression. European Journal of Immunology. 39(9):2571-83. PMID:19701891
  38. Lance M. Relland, Manoj K. Mishra, Dipica Haribhai, Brandon Edwards, Jennifer Zeigelbauer, and Calvin B. Williams (2009). Affinity-based selection of regulatory T cells occurs independently of agonist-mediated induction of Foxp3 expression. Journal of Immunology. 182(3):1341-1350. PMCID: PMC2818884

Book Chapters (2009-Onwards)

  1. Shriti Singh, Manoj Kumar Mishra, and Rajesh Singh (2018). Epigenetic Modulations in Ovarian Cancer. Elsevier publication, Saldanha S. Ed. 2018, P169–193.
  2. Sanjay Kumar, Rajesh Singh, Manoj K. Mishra (2018). Genetic and Epigenetic Modifications in Pancreatic Cancer. Elsevier publication, Saldanha S. Ed. 2018, Pages 117–140.
  3. Sanjay Kumar, James A. Stokes III, Udai P. Singh, and Manoj K. Mishra (2016) Ezh2, an epigenetic regulator: The future of prostate cancer treatment. In: Epigenetic Advancements in Cancer. Editors-Mishra and Bishnupuri, Springer International Publishing AG, Gewerbestrasse 11, 6330 Cham, Switzerland, 2016; p229-245.
  4. James A. Stokes III, Sanjay Kumar, Karyn Scissum-Gunn, Udai P. Singh, and Manoj K. Mishra (2016) Epigenetic and cancer: An evaluation of the impact of dietary components. In: Epigenetic Advancements in Cancer. Editors-Mishra and Bishnupuri, Springer International Publishing AG, Gewerbestrasse 11, 6330 Cham, Switzerland, 2016; p65-78.
  5. Kumar S Bishnupuri and Manoj K. Mishra (2016) Epigenetics of Colorectal Cancer. In: Epigenetic Advancements in Cancer. Editors-Mishra and Bishnupuri, Springer International Publishing AG, Gewerbestrasse 11, 6330 Cham, Switzerland.
  6. James A. Stokes III and Manoj K. Mishra (2014) Role of resveratrol (RES) in regenerative medicine. In: Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering. IGI Global, Hershy, PA Chapter 18, pages 392-402.
  7. Shree Ram Singh, Manoj K. Mishra and Chhavi Chauhan (2012) Cell Transplantation in Chronic Kidney Disease. In: Cell Transplantation: New Research, Nova Science Publisher, Inc., New York, 978-1-62100-542-1, Page 1-24.
  8. Shree Ram Singh, Manoj K. Mishra, Maduri Kango-Singh and Steven X. Hou (2012) Generation and Staining of Intestinal Stem Cell Lineage in Adult Midgut. Methods in Molecular Series, Somatic STEM cells: Methods in Molecular Biology, 879: 47-69.
  9. Shree Ram Singh and Manoj K. Mishra (2012) JAK/STAT Signaling in Cell Fate and Tumorigenesis. In: Signaling, gene regulation and cancer, Nova Science Publisher, Inc., New York, ISBN: 978-1-61942-092-2, Chapter 4, pages 63-72.