Shreekumar R. Pillai

dr. shreekumar

SHREEKUMAR R. PILLAI, Ph.D.

Professor of Biology
and Supervisor
Mathematics and Science Tutorial Center 

Phone: 334-229-7501
e-Mail: spillai@alasu.edu

 

 

 

 

 

 

 

Research

Nanogenomic evaluation of antimicrobial effects of proprietary peptides, silver coated carbon nanotubes and their conjugates with peptides, SPIONS coated with antibacterial peptides, carbon nanotube FET biosensors for pathogen detection, targeted drug delivery, PCR/qPCR based detection of foodborne pathogens, development of mucosal and DNA vaccines for RSV and Chlamydia, siRNA and metal nanoparticle based therapeutics for viral pathogens 

 

Education/Training

           

Auburn University
 

Ph.D.  

1992      

Veterinary Medicine

Bombay Veterinary College   
 

M.V.Sc.   

1987

Food hygiene and Public health

Bombay Veterinary College

B.V.Sc.  

1984

Veterinary Medicine

 

Professional
Appointments

 

   Current:     

Professor of  BiologyISupervisor,
Mathematics and Science Tutorial Center,
Alabama State University,
Montgomery, AL

2002-2003: 

Post-Doctoral Research Fellow,
Dept. of Biological Sciences,
Alabama State University,
Montgomery, AL

2001-2002

Post-Doctoral Research Fellow,
Dept. of Biological Sciences,
Auburn University,
Auburn, AL

1998-2000

Post-Doctoral Research Associate,
Dept. of Veterinary Science,
Pennsylvania State University, 
University Park, PA

1997-1998

Product Manager,
Wockhardt Veterinary Ltd.,
Mumbai, India

1995-1997

Product Executive,
Cyanamid India Ltd., 
Mumbai, India

1993-1995

Technical Services Manager,
Damania Pharma Ltd.,
Mumbai, India

1988-1992

Graduate Research Assistant,
Auburn University, 
Auburn, AL

1987-1988

Graduate Research Assistant,
Louisiana State University,
Baton Rouge, LA 

1986-1987

Assistant Professor,
Bombay Veterinary College,
Mumbai, India

1985-1986

Research Assistant,
Bombay Veterinary College,
Mumbai, India             

Recent Publications (11 selected from 56)

Ejovwoke Dosunmu, Atul Chaudhari, Shree R. Singh, Vida A. Dennis, and Shreekumar R. Pillai. 2015. Silver coated carbon nanotubes down-regulate the expression of Pseudomonas aeruginosa virulence genes: a potential mechanism for their antimicrobial effect.  http://dx.doi.org/10.2147/IJN.S85219. International Journal of Nanomedicine 10: 5025—5034

Chaudhari AA, Jasper SL, Dosunmu E, Miller ME., Arnold RD., Singh SR., Pillai SR. Journal of Nanobiotechnology. 2015. Pegylated silver coated carbon nanotubes are non-toxic to eukaryotic cells and destroy Salmonella by regulating structural, metabolic and virulence associated gene expression. Journal of Nanobiotechnology 2015, 13 :23 (22 March 2015)

Pooja M Tiwari, Erdal Eroglu, Swapnil S Bawage,  Komal Vig, Michael  E Miller, Shreekumar R. Pillai,  Vida A Dennis, Shree R Singh. 2014. Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis virus. Biomaterials. 2014.   35(35): 9484-94. doi:10.1016/ j.biomaterials.2014.07.032.

Michael W. Chien*, Robert R. Johnson, Shreekumar R. Pillai, Shree Ram Singh, and A.T. Charlie Johnson, Jr. 2014. Mechanics and energetics of DNA hybridization on single-walled carbon nanotubes explored using adaptive biasing force calculations. J. Physical Chemistry C.118, 2209−2214.

Swapnil Bawage, Pooja Tiwari, Shreekumar R. Pillai, Vida A. Dennis and Shree R. Singh. 2013. Recent Advances in Diagnosis, Prevention, and Treatment of Human Respiratory Syncytial Virus. Advances in Virology. doi:10.1155/2013/595768.

Cemil Boyoglu, Qingwen He, Gerold Willing, Seyhan Boyoglu-Barnum, Vida A. Dennis, Shreekumar Pillai, and Shree R. Singh. “Microscopic Studies of Various Sizes of Gold Nanoparticles and Their Cellular Localizations. Nanotechnology. 2013. doi:10.1155/2013/123838 

Sapna Jain, Shree R. Singh, Shreekumar Pillai 2012. Toxicity Issues Related to Biomedical Applications of Carbon Nanotubes. The Journal of Nanomedicine & Nanotechnology. 3: 140. Doi: 10.4172/2157-7439.1000140.

Sapna Jain, Shree R. Singh, Daniel W. Horn, Virginia A. Davis, Manoj Kumar Ram, Shreekumar Pillai. 2012. Development of an antibody functionalized carbon nanotube biosensor for foodborne bacterial pathogens. Biosensors and Bioelectronics. S11:002. Doi: 10.4172/2155-6210.S11-002.

M. A. Taha, Shree R. Singh, Kara Hulett. Shreekumar R. Pillai, R. Agee, Vida A. Dennis. 2011. A peptide containing T-Cell epitopes of Chlamydia trachomatis recombinant MOMP induces systemic and mucosal antibody responses in mice. World journal of Vaccines. 1: 138-147.

Subbiah Alwarappan, Shree R Singh, Shreekumar Pillai and Ashok Kumar. 2012. Direct Electrochemistry of Glucose Oxidase at a Gold Electrode Modified with Graphene Nanosheets. Analytical letters. 45:7, 746-753

Mitchell Lerner, Brett Goldsmith, Ronald McMillon, Jennifer Dailey, Shreekumar Pillai, Shree R. Singh, A.T. Charlie Johnson. 2011. A Carbon Nanotube Immunosensor for Salmonella. AIP Advances. 1, 042127 (2011); doi: 10.1063/1.3658573.

 

Relevant Presentations

Sturdivant, S., Pillai, S.R., Singh, S.R. 2006. Evaluation of a
             Piezoelectric Immunosensor to Detect Salmonella typhimurium.
             Poster # P-073. ASM 106th General Meeting, May 21-May 25,
             Orlando, FL. Session No.: 240/P.

Lane-Carter, C. ,Pillai, S. R. , Dennis, V. A., Singh, S. R.. 2006.
             Poster #E031.Genetically Modified CT-Based Recombinant
             RSV Immunogens and their Immune Response. ASM
             106th General Meeting, May 21-May 25,
             Orlando, FL. Session No.: 060/E.  

Sturdivant, S., Pillai, S.R., Singh, S. 2005. Abstract # 05-A-882-
             ABRCMS. Evaluation of a Piezoelectric Immunosensor to
             Diagnose Salmonella typhimurium. ABRCMS. Nov 2-5. 
             Atlanta, GA.

 

Books

Khot, J. 8., Sherikar, A.T, Jayarao, B. M, and Pillai, S. R. 1987. Advances 
             in Meat Research. Red and Blue Cross Publishers, Parel, 
             Mumbai - 400012, India

 

Synergistic Activities

  • Serve as STEM biology faculty
  • Member, Curriculum enhancement committee to revise biology curriculum
  • Member, grantsmanship committee
  • Member, research and publications committee
  • Serve on USDA ad-hoc review panel

 

Students/Personnel Trained

Summer high school apprentice students: 

Shandrea Jackson, Arshasmine Tellis, Simone Holmes: Poster title: Rapid Detection of Salmonella enterica serovar Typhimurium by PCR. Third place award.

Alicya Blackman, and Ashley Cochran: Poster title: Cloning the full length RSV F gene into pET32 shuttle vector. 2007 summer science apprenticeship program held at the Embassy suites hotel, Montgomery, July, 2007.

Jonathan Davis and Crystal Smith: Poster title: Evaluation of a piezoelectric immunosensor to detect Salmonella enterica serovar Typhimurium from milk and chicken broth. First prize at the 2006 summer science apprenticeship program held at the Embassy suites hotel, Montgomery on Friday, July 28, 2006.

9 HBCU-UP STEM scholars mentored –Tanisha Hutchinson, Ashleigh Brown,  Monica Hodge, Dylan Williams, Carol Harden, Jorrell Fredericks, Anamika Mishra, Donchel Boone, Vincent Onilyo.

Member advisory committee:

Stacie Sturdivant  -  M.S. Biological Sciences, Charee Bennett - M.S. Biological Sciences, Kara Hulett – M.S. Biological Sciences, Naomi Abrams – M.S. Biological Sciences, Clifford Youngblood – M.S. Biological Sciences, Courtnee Bell – M.S. Biological Sciences, Nicole LaRue - M.S. Biological Sciences, Deandra Ashmore – PhD, Biological Sciences, Swapnil Bawage - PhD, Biological Sciences, Skyla Duncan - PhD, Biological Sciences

Major advisor:

1. Angel Hundley – M.S. Biological Sciences 2009 – Antimicrobial effects of Silver coated carbon nanotubes

2. Shanese Lani Jasper – MS Biological Sciences 2015 – Silver PVP coated with proprietary peptides for treatment of Salmonella

3.  Ejovwoke Dosunmu - PhD Biological Sciences 2015 – Alternative antimicrobial and anti-inflammatory agents against pseudomonas aeruginosa infection

Post-doctoral fellows mentored:

Atul Chaudhari, Kauser Hussain, Sapna Jain, Komal Vig, Akhilesh Kumar, Lekha Adiani, Ronald McMillon, Madhuri Chilakapati

Professional Memberships

1. International Association of Food Protection

2. American Society for Microbiology

3. National Association of Biology Teachers

4. AAAS

Collaborations

  • Auburn University (Dr. Martin)

  • Louisiana State University (Dr. Venugopal)
  • Pennsylvania State University (Dr. Jayarao)
  • Tulane National Primate Research Center  (Dr. Dennis)
  • University of South Florida (Dr. Kumar)